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Nicotine could contribute to this progression by aggravating vasoconstriction, although other tobacco smoke toxins are also likely to be contributing to progressive vascular injury. In laymans terms this tells us that nicotines impact as a vasoconstrictor (shrinking blood vessels which increases blood pressure) can contribute, alongside the other chemicals in cigarette smoke, to more severe conditions brought about by prolonged hypertension

Worn-down enamel (the outer layer of your teeth)

Common Nicotine Withdrawal Symptoms Cravings Irritability & Anxiety Trouble Sleeping Increased Appetite Brain Fog How Long Does Nicotine Withdrawal Last

PMID 25572196